Fisetin and its Health Benefits

Indulging in a refreshing fruit bowl or enjoying a delicious salad can be one the best ways of feeling good on the inside and out and meeting your nutritional needs and requirements. 

In fact, fresh fruits and vegetables are a great source of nutrients, micronutrients, and antioxidants that help you maintain a clean bill of health. 

Another reason to enjoy these gifts of nature is for their delicious flavor resulting from naturally occurring bioactive flavonoids. 

Fisetin is a flavonoid often found in fruits and vegetables like apples, peppers, tomatoes, strawberries, onions, grapes, and cucumbers. 

Naturally occurring flavonoids like fisetin are a rich source of antioxidants that help scavenge free radicals and prevent serious health risks along with anti-inflammatory properties. 

Furthermore, antioxidants also help reduce the damage that can be caused by the oxidation process in the body. 

With a sudden rise in fitness culture, many people are beginning to utilize healthy supplements to enhance their overall health. 

Fisetin is one such supplement approved by scientists and enjoyed by the masses for its antioxidant, anti-aging, and anti-inflammatory properties. 

If you are someone who is interested in incorporating fisetin supplements into their diet plan but does not know where to begin, do not worry. 

Here is a comprehensive guide to using fisetin supplements along with its wonderful health benefits.

What is Fisetin?

Fisetin is a naturally occurring plant polyphenol that is also a part of the flavanol subcategory. 

In simpler terms, Fisetin is a naturally occurring bioactive flavonoid that is generally found if flavorful fruits and vegetables. 

Traditionally, fisetin is a yellow or ochre-colored flavonoid that not only gives fruits and vegetables their taste but also their pigment.

According to researchers and scientists, fisetin has been known to contain exceptional antioxidant and anti-inflammatory properties. 

The first recorded use of isolated fisetin was recorded back in 1833 which was extracted from a smoke bush called Rhus Cotinus. 

The basic chemical characteristics of fisetin were further defined in 1886 by a scientist named J. Schmidt. 

According to researchers and scientists, fisetin has been known to contain exceptional antioxidant and anti-inflammatory properties. 

By the 1890s the chemical structure of fisetin was defined by a scientist named S. Kostanecki through a process called chemical synthesis. 

Fisetin is widely celebrated by good communities and healthcare experts for its senolytic properties.

What are Senolytic Cells?

Senolytic cells are a class of smaller molecules that help induce the reduction or death of senescent also known as deteriorating cells. 

Senescent cells or deteriorating cells begin to develop as you start to age. This is because with progressing age your body becomes incapable of developing and dividing cells. 

Instead, the body begins to develop an inflammatory substance called senescent that attack other neighboring cells. 

According to some studies, there has been evidence of the relationship between senolytic cells and the number of senescent cells in the body. 

This is because senolytic cells help repair the damage caused by the senescent cells due to their anti-inflammatory properties.

Foods that contain Fisetin:

Fisetin is a naturally occurring bioactive plant pigment that belongs to the flavonoid subcategory. 

This flavonoid is naturally found in naturally occurring food items and is ideally a part of your favorite fruits and vegetables. 

Here is a list of foods along with the fisetin contents you can incorporate into your diet plan to achieve the benefits of fisetin:

Foods	Amount in  µg/g
Strawberries	160
Apples	26.9
Grapes	3.9
Onions	4.8
Kiwi	2.0
Lotus root	5.8
Cucumber	0.1
Peaches	0.6
Persimmon	10.6

What are the Benefits of Fisetin?

According to a study, out of 10 compounds that were tested, fisetin was proven to be among the most efficient and powerful senolytic to eliminate senescent cells ad reduce inflammation. 

Another study indicates that fisetin helps boost your overall health and immunity as it integrates powerful antioxidants. 

If you are someone who is willing to incorporate fisetin-rich foods or fisetin supplements into your diet plan, we’ve got you covered.

Here is a list of benefits of consuming fisetin that will definitely help seal the deal for you:

Senolytic Activities:

According to research led by Lancet, fisetin has been proven to induce senolytic activity in both mice and human tissues. 

Furthermore, fisetin works to prevent further cell damage and damage to the DNA caused by senescent cells in the body during the aging process. 

In a study that compared 10 compounds including resveratrol, luteolin, curcumin, fisetin, and rutin, fisetin was among the strongest senolytic cell.

Rich in Antioxidants:

Free radicals can lead to severe health repercussions that can lead to cell damage, lipid damage, amino acids, and nucleic cell damage.  

According to research, fisetin has been regarded as a great source of antioxidants and has the ability to scavenge free radicals in the bloodstream.

Reduces Inflammation:

If you are looking for a great way of reducing inflammation in the body then it is best to load up on foods that are rich in fisetin like strawberries. 

Fisetin has been known to visibly reduce inflammation as it possesses strong anti-inflammatory properties.

Facilitates Healthy Aging:

Believe it or not, fisetin has amazing senotherapuetic properties that help aid the healthy aging process and may help extend your lifespan.

According to research, that helps reduce oxidative stresses and increase the levels of an antioxidant called glutathione in the body.

Enhances Heart Health:

Fisetin might also help boost and enhance your cardiovascular health in multiple ways. 

According to a report, antioxidants like fisetin can help induce the cardiac regenerative process by activating the genes that are involved in cell proliferation.

Reduces the risk of cancer:

According to the data collection, fisetin possesses antiproliferative properties that help reduce the risk of developing cancers by inhibiting the cell growth of tumors.